The RESEPI (Remote Sensing Payload Instrument) GEN-II payload is an advanced, next-generation, sensor-fusion platform designed for accuracy-focused real-time and post-processed aerial, mobile, and pedestrian-based remote sensing applications. RESEPI GEN-II utilizes the Inertial Labs’ Dual Antenna Inertial Navigation System (INS-D), a high-performance and expandable navigation system powered by Inertial Labs’ Extended Kalman Filter (EKF). Within this system lies a Tactical Grade Inertial Measurement Unit (IMU), the Kernel-210, also by Inertial Labs. It provides more expandability over its predecessor by offering end-users and integrators the ability to integrate their platforms by taking advantage of built-in software integrations made by MAVLink and DJI’s Payload SDK (PSDK). Benefit from two new camera options with a wider field of view, faster shutter speeds, and higher resolution images. Field-swappable mounts and accessories easily integrate with platforms like the WISPR Ranger Pro 1100, Freefly Astro, Sony Airpeak S1, and DJI M350. The RESEPI GEN-II platform features a more powerful on-board computing module for real-time point cloud visualization and further integrations with external/additional sensing modules, giving users the ability to integrate and synchronize their additional cameras and LiDAR or input-aiding data to the navigation filter from wheel speed sensors, encoders, external IMU’s or Air Data Computers (ADC). This payload is perfectly suited for plug-and-play with end-users and engineering firms looking to adopt a hardware package that offers customization and expandability with a versatile remote sensing solution.